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     美研究說抗癌新藥研發成本遠低于行業估計

      中化新網訊 抗癌新藥常被定出“天價”,制藥企業辯護的一大理由是研發成本巨大。但美國11日公布的一項新研究說,研發一種抗癌新藥只需6.5億美元左右,遠低于制藥行業廣泛援引的數字,而上市后的收入卻相當可觀。

      制藥界的常見說法是,一種新藥從研發到上市需要10年和10億美元。2014年,美國塔夫茨藥物研發研究中心發表一份受藥企資助的研究說,新藥的研發成本已從2003年的約8億美元增至26億美元。

      為了更好地估計新藥研發成本,美國俄勒岡衛生科學大學和斯隆—凱特林癌癥研究中心的研究人員采取一種新的分析方法,重點研究了各有一種抗癌藥獲批上市的10家公司的研發成本,結果“驚訝地”發現,一種抗癌新藥從研發到上市所用時間的中值為7.3年,而成本中值是6.48億美元。

      這項發表在《美國醫學會雜志·內科學卷》上的研究說,這10種抗癌新藥上市時間中值為4年,總銷售收入已達670億美元,而總研發成本僅為72億美元。

      “這個利潤真是特別巨大,”參與研究的俄勒岡衛生科學大學助理教授維奈·普拉薩德在一份聲明中說,“在不損害創新的情況下,藥價還有下降空間嗎?在我看來,答案是肯定的。”

      《美國醫學會雜志·內科學卷》同期配發的一篇評論文章說,制藥行業一直是美國利潤最高的行業,這表明專利獨占性提供的定價能力所帶來的價值遠遠超過制藥研發的固有風險。

      該評論得出結論說:“現在這項研究的意義很清楚。目前制藥行業的定價政策與研發成本無關。政策制定者可以安全地采取措施遏制藥價,而不用擔心損害創新。”

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